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Partnership with Harmony Biosciences to Develop and Commercialize CSTI-100 (now HBS-102) 

August 9, 2021

We are very excited to announce the signing of a partnership agreement with Harmony Biosciences.  Under the terms of the agreement, Harmony Biosciences will acquire the full development and commercialization rights globally, with the exception of Greater China, of CSTI-100 (now HBS-102), a Melanin Concentrating Hormone Receptor 1 (MCHR1) antagonist.  HBS-102, a potential first-in-class molecule with a novel mechanism of action, has the potential to offer a novel approach to the treatment of narcolepsy including the symptoms of Rapid Eye Movement (REM) sleep dysregulation, such as cataplexy, hallucinations, and sleep paralysis. The financial terms include an upfront payment of $3.5 million and potential development and regulatory milestone payments and royalties. Please also see the press release from Harmony.